Some configuration changes require the cache to be cleared on Responder for the settings to take effect.
The cache files are located in two different locations, depending on the applications ran. The locations are:
C:\Users\[User]\AppData\Local\Miner and Miner\Responder\Cache
C:\Users\[User]\AppData\Roaming\Miner and Miner\Responder
The applications that run on the computer need to be stopped first, including all server processes if it's the application server that is being cleared.