The following error occurs when opening a new design in ArcMap:
The design could not be loaded. None of the layers in this stored display or map document have a data source.
This is caused by bug MM50103. Occurs when a stored display contains layers from two different databases in the same SQL Server instance.
Move layers to same database or database in another SQL Server instance. Bug MM50103 has been submitted for this issue, and has been fixed in ArcFM 10.1.1. If you are using ArcFM 10.0.2, there is also an ArcFM 10.0.2 patch for this issue. Simply install the latest ArcFM Desktop 10.0.2 patch to get this bug fix.